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  Piperacillin

Pharmacokinetics | Indications | Routes of Administration and Dosage | Contra Indications | Precautions | Interactions | Brand Names


Systems General (Systemic)
Category Antibacterial


Pharmacokinetics

Piperacillin is acid sensitive. It is eliminated by glomerular filtration & tubular secretion in the kidneys.



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Indications

It has broad spectra of activity & acts against all Gram Positive & Gram Negetive Organisms except those that produces Beta lactamase. It is very effective against Pseudomonas.



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Routes of Administration and Dosage

Adults: In severe infection 12-18 gm/day in 4 equal doses. Children: 100- 300 mgs/kg/day in 4 divided doses.



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Contra Indications

Contraindicated in pregnancy, hypersensitivity to piperacillin.



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Precautions

Precaution to be taken while taking cephalosporins.



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Interactions

Piperacillin clearance is reduced by Probenecid.



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Brand Names

Pripracil (Wyeth Lederle), Piprapen(FDC).



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Pharmacokinetics | Indications | Routes of Administration and Dosage | Contra Indications | Precautions | Interactions | Brand Names

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