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  Vitamin B1 (Thiamine)

Pharmacokinetics | Indications | Routes of Administration and Dosage | Contra Indications | Precautions | Interactions | Brand Names


Systems General Systemic
Category Water soluble vitamin.


Pharmacokinetics

Physiological amounts are absorbed by active transport. If large doses are given orally, some amount of passive diffusion occurs. Small amounts are stored in the body tissues. It is rapidly excreted in the urine.



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Indications

It is used in the treatment of thiamine deficiency known as Beri-Beri. A daily regular intake of thiamine is necessary to avoid deficiency disorders.



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Routes of Administration and Dosage

Prophylatically: infants, pregnant women, in chronic diarrhoea, parenteral alimentation = 2-10 mg/day. To treat Ber-Beri: 100 mg/day IV or IM. Neurological symptoms in chronic alcholics: 100 mg/day parentrally.



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Contra Indications

It is a relatively safe drug and usually free from adverse effects.



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Precautions

Hypersensitivity reactions may rarely occur on parenteral injection.



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Interactions

Interactions with other drugs are usually rare.



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Brand Names

BERIN, BENEURON, BETABION.



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Pharmacokinetics | Indications | Routes of Administration and Dosage | Contra Indications | Precautions | Interactions | Brand Names

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